Used for the separation and analysis of organic small molecules and lipids. Compared to silica made from silicates (such as the F brand), Bonnasil-BS silica, produced through the sol-gel process, offers significant advantages in normal-phase applications. Its high purity and through-pore structure effectively reduce tailing and irreversible adsorption while improving the recovery rate—all at a comparable cost for customers.
| Base | Silica | |
|---|---|---|
| Shape | Spherical | |
| Metal content | ＜30ppm | |
| Particle size | 8/10/15/30μm | |
| Pore size | 100Å | 120Å |
| Bonding phase | - | - |
| Operating pressure | ＜20MPa | ＜20MPa |
| Max.pressure | ＜40MPa | ＜40MPa |
| Pore volume | ~ 1.0 mL/g | ~ 1.0 mL/g |
| Specific surface area | ~ 400 m2/g | ~ 320 m2/g |
| Bulk density | ~ 0.50 g/mL | ~ 0.50 g/mL |
| Carbon content | - | - |
| pH range | 2-8 | 2-8 |
Purification Performance comparison
Flash Purification Conditions:
Sample: Ciclosporin
Mobile Phase: Ethyl acetate
Flow Rate: 8mL/min
Sample Loading: 0.5g in 5mL Ethyl acetate
Detector: UV@ 214 and 254 nm
| Purity | Yield | |
|---|---|---|
| Bonnasil-BS Spherical Silica 30, 100Å, 20g | 99.20% | 86% |
| Brand F Spherical Silica 30, 100Å, 20g | 98.70% | 61% |
